1,482 research outputs found

    BIM: a technology acceptance model in Peru

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    The purpose of this paper is to empirically study factors that facilitate the adoption of building information modelling (BIM) among practitioners using the unified theory of technology acceptance model (TAM). The factors identified in the TAM were examined using a quantitative approach. The empirical investigation has been conducted using a survey questionnaire. The data set has been obtained from 73 architects and engineers in Peru. Results show that Perceived Usefulness (PU) is the most important determinant of Behavioural Intention (BI), while Perceived Ease of Use (PEOU) is found to have no significant effect on BI. The findings provide an excellent backdrop in the development of policy and a roadmap for BIM implementation in Peru. The original contribution and value of the paper is the use of TAM to provide empirical evidence on factors that facilitate BIM adoption in Peru

    Evolution in public procurement and the impact of e-procurement platforms: a case study

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    A Work Project, presented as part of the requirements for the Award of a Masters Degree in Management from the NOVA – School of Business and EconomicsThe aim of this project is to understand the evolution that occurred in the public procurement due to the new Public Contracts Code that changed the procurement procedures and forced public entities to use electronic procurement platforms. This work is a contribution to the understanding of the main procurement changes with this new code as well to understand the impact and functioning of electronic procurement platforms. Moreover, a case study is presented, using the Centro Hospitalar Lisboa Norte, to assess the impacts of these changes and the inevitable adjustments needed

    Strategic group mapping and strategy canvas analysis of the environmental consulting sector : a project-based dissertation on the German Market : a public archival data web-content analysis

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    Nesta dissertação na modalidade de projeto tive a oportunidade de entrar em contacto com uma Pequena Média empresa no setor de consultoria ambiental, onde me foi pedido para realizar uma análise à competição no mercado alemão, focando-me em mercados específicos em que a empresa se planeia especializar (Nanomateriais, Biocidas e Instrumentos Médicos). É possível observar que as leis ambientais mais restritivas, desenvolvimentos dentro da química e consciência ambiental estão a criar um grande potencial para crescimento e relevância deste setor. Gestão estratégica e categorização estratégica desenvolveram muitas correntes de pesquisa e no entanto, ferramentas estratégicas ainda não foram utilizadas para analisar o setor da Consultoria ambiental, que tem sido negligenciado na literatura. Através de uma análise de dados de arquivamento públicos (websites, páginas de LinkedIn, e relatórios anuais), foi possível aplicar ferramentas estratégicas (Mapeamento de grupos estratégicos e o Canvas estratégico) a uma amostra de 57 empresas de consultoria ambiental no mercado alemão assim como recolher sinais de competitividade e tamanho das empresas. Nesta análise pode-se comprovar que a revolução digital, sustentabilidade e responsabilidade corporativa já se encontram presentes nesta indústria, que várias empresas oferecem tanto apoio ambiental com foco regulatório e de gestão como um apoio ambiental com foco cientifico, procurando eficiência ambiental e redução de desperdício, e que nanomateriais parecem ser o mercado menos presente em websites, comparativamente com o mercado dos biocidas e dos instrumentos médicos. Este trabalho permitiu demonstrar o valor que ferramentas estratégicas podem ter, mesmo quando aplicado a informação publica, neste caso de websites, e também demonstrar as respetivas limitações, permitindo-nos ter uma melhor visão das nuances estratégicas e estrutura de um setor negligenciado. Para além disso, o contexto da análise estratégica também demonstra que o Brexit pode agir como um catalisador de expansão geográfica, o que é um impacto estratégico que ainda não tinha sido estudado previamente em empresas nesta indústria.In this project-based dissertation I had the chance to work with an environment consulting SME, where I was asked to do a competitor analysis of the German Market in particular sectors in which they will focus on (Nanomaterials, Biocides and Medical Devices). It is possible to observe that the increasingly stringent environmental policies, chemistry developments and environmental consciousness are creating a great potential for the growth in size and relevance of this sector. Strategic management and strategic categorization have developed into many streams of research, and however, strategic tools still haven’t been used to describe the environmental consulting sector, which has been overlooked in the literature. Through an analysis of public archival data (Company website, LinkedIn and annual reports), it was possible apply the Strategic group mapping and Strategy canvas frameworks to a sample of 57 environmental consulting companies in the German market, as well as to collect other signs of competitiveness and size. In this analysis it was found that the digital revolution, sustainability and corporate responsibility are already present in this industry, it was found that many companies are providing not only environmental regulatory and managerial support but at the same time providing scientific support, focusing on environmental efficiency and waste management, and that nanomaterials seem to be the least featured market in companies websites comparatively to biocides and medical devices. This paper allowed to demonstrate the value that strategic tools can have, even when applied to public website-content, as well as to demonstrate their limitations, allowing us to give a better overview of the strategic nuances and structure of an overlooked sector. Moreover, the context of this company’s strategic analysis also showcases that Brexit can act as a catalyst of geographical expansion, which is a strategical impact in this industry that hasn’t been studied before for companies in this industry

    The humanized territory and its planning

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    Peer Reviewe

    altered expression of cD300a inhibitory receptor on cD4+ T cells From human immunodeficiency Virus-1-infected Patients: association With Disease Progression Markers.

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    The ability of the CD300a inhibitory receptor to modulate immune cell functions and its involvement in the pathogenesis of many diseases has aroused a great interest in this molecule. Within human CD4+ T lymphocytes from healthy donors, the inhibitory receptor CD300a is differentially expressed among different T helper subsets. However, there are no data about the expression and regulation of CD300a receptor on CD4+ T cells from human immunodeficiency virus (HIV)-1-infected patients. The objective of this study was to investigate the expression of CD300a on CD4+ T cells from HIV-infected patients on suppressive combined antiretroviral therapy (cART) and cART naïve patients. Our results have demonstrated that the expression levels of this inhibitory receptor were higher on CD4+ T cells from HIV-1 infected subjects compared with healthy donors, and that cART did not reverse the altered expression of CD300a receptor in these patients. We have observed an increase of CD300a expression on both PD1+CD4+ and CD38+CD4+ T cells from HIV-1 infected people. Interestingly, a triple positive (CD300a+PD1+CD38+) subset was expanded in naïve HIV-1 infected patients, while it was very rare in healthy donors and patients on cART. Finally, we found a negative correlation of CD300a expression on CD4+ T lymphocytes and some markers associated with HIV-1 disease progression. Thus, our results show that HIV-1 infection has an impact in the regulation of CD300a inhibitory receptor expression levels, and further studies will shed light into the role of this cell surface receptor in the pathogenesis of HIV infection

    Sensing the difference: the influence of anisotropic cues on cell behavior

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    From tissue morphogenesis to homeostasis, cells continuously experience and respond to physical, chemical and biological cues commonly presented in gradients. In this article we focus our discussion on the importance of nano/micro topographic cues on cell activity, and the role of anisotropic milieus play on cell behavior, mostly adhesion and migration. We present the need to study physiological gradients in vitro. To do this, we review different cell migration mechanisms and how adherent cells react to the presence of complex tissue-like environments and cell-surface stimulation in 2D and 3D (e.g. ventral/dorsal anisotropy)

    HULL’S MANUFACTURING COST STRUCTURE

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    This study analyses the structure of costs of several processes associated with the shipbuilding industry. The analysed productive processes are: cutting preparation procedures, steel plate cutting processes, processes of hull plates and stiffeners forming, associated transportation and assembling of plates and profiles, and finally the welding processes. The methodology allows a shipyard to identify the main costs related to the manufacturing of the hull and the aspects that should be improved for increase productivity. The methodology adopted may easily be adapted by each shipyard creating a work database in order to improve and update these formulas by adding new corrective coefficients based on the type of the built ship or construction complexity of certain ship blocks. It is analysed 2 independent case studies that took place at different Portuguese shipyards and covering different aspects of the steel hull shipbuilding processes. The first case study considers time and cost analysis of cutting preparation processes made by the design office, cutting/marking of steel plates and forming processes of stiffeners and hull plates, required for the construction of an 83m Hopper Barge, built by MPG, at LISNAVE Mitrena Shipyard, Portugal, 2010. The second case considers the time and cost analysis of stiffeners cutting, steel plates and stiffeners assembly and welding, associated with the building of several blocks of an 80m fisheries supporting vessel by JOPERINOX Shipyard at Alverca, Portugal, 2008

    Julio Cabilla Alberto, assistants in medicine and surgery and journalist from Cadiz (1897 - 1955)

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    La historiografía de la Enfermería Gaditana nos remite a los orígenes de su organización colegial, principios del siglo XX. Los datos obtenidos para la reconstrucción histórica profesional proceden principalmente de la revista que el Colegio de Practicantes editó desde 1916 a 1939, publicación que vio la luz gracias a profesionales de merecido reconocimiento como Julio Cabilla Alberto, quien a pesar de su juventud asumió la dirección de El Practicante Gaditano y su puesta en marcha. Su biografía se fundamenta en fuentes primarias documentales, como es el expediente personal (Archivo Diocesano Cádiz) y el académico depositado en el Archivo de la Universidad de Cádiz.The historiography of the nursing Cádiz refers us back to the origins of your organization associative, beginning 20th century. The data obtained for the historicall reconstruction profesional come mainly from the magazine published by the Association of Medical Assistants in medicine and surgery from 1916 to 1939, publication that saw the light tranks to professionals of deserved recognition as Julio Alberto Cabilla, who, despite his youth, took the address of El Practicante Gaditano and its commissioning. His biography is based om documentary primary sources as it is the personal record (File Diocesan Cádiz) and academic deposited in the University of Cádiz Archive

    Políticas urbanas: tendencia de transformación en el área de influencia de grandes proyectos

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    Este artículo analiza la tendencia de transformación en el área de influencia, en donde se circunscriben Grandes Proyectos Urbanos (GPU´s), y la caracterización de los atributos urbanos de la zona. Esta caracterización se revisa en el análisis de la tendencia de los usos de suelo actual, así como en los permisos y licencias de construcción de las zonas aledañas a los proyectos, los valores inmobiliarios y las variables que fueron relevantes en la aplicación de un análisis de correlación. Como caso de estudio se presenta el área central de la ciudad, en donde se han realizado varias políticas relacionadas con GPU´s, como; la Macro Plaza de Monterrey, efectuada en el año 1985 y el Paseo Santa Lucia, realizado en el año 2007, así como también el área decretada como patrimonio histórico de la ciudad en el año 1993, denominada Barrio Antiguo, entre otras. En esta área central, se evaluaron los atributos urbanos de diferentes variables, de las dimensiones jurídico-espaciales, la dimensión de accesibilidad urbana y la de jerarquía urbana. Estos proyectos urbanos generaron gran cantidad de espacios verdes y lugares de esparcimiento en el área central cuando fueron implementados, así como la protección del patrimonio histórico de un área específica del primer cuadro, dando lugar a una situación dual entre la determinación de Centro Histórico y Centro Urbano (Distrito de negocios) de esta área de la ciudad. Siendo los usos de suelo y su variabilidad los factores relevantes actualmente. Con el análisis de tendencia y caracterización de las zonas, se plantean posibles caminos que puede seguir el desarrollo urbano de esta área de la ciudad, ayudando al proceso de planificación de la zona

    La radio como instrumento de rehabilitación y recuperación en trastorno mental severo y crónico: experiencias en la Comunidad de Madrid

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    En este texto se exponen los resultados parciales de una investigación realizada sobre los usos de la radio como instrumento de rehabilitación y recuperación de personas diagnosticadas con trastorno mental severo y crónico en entornos comunitarios. El ámbito geográfico del estudio es la Comunidad Autónoma de Madrid en la que se han analizado un total de veinte programas de radio producidos por personas con trastorno mental severo y crónico. Estos programas se difunden a través de la antena de emisoras comunitarias, de sus páginas webs y de otras vías de difusión por Internet. Nuestro análisis ha combinado diversas metodologías de carácter cualitativo como la observación directa, la escucha de los programas y la realización de entrevistas en profundidad con terapeutas y pacientes, con el objetivo de determinar los factores más importantes que determinan el éxito terapéutico de estas experiencias. Una de las conclusiones que se constatan es que existe una gran heterogeneidad pudiendo identificarse diferentes modelos de aplicación. Existen proyectos radiofónicos vinculados a programas públicos de salud mental, mientras otros son impulsados por asociaciones u instituciones de carácter privado. El papel que desempeñan las personas que padecen los trastornos así como el de sus coordinadores-terapeutas en el proceso de producción y difusión de los programas también registra diferencias significativas en los casos de estudio
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